The land for the Avraham Avinu Neighborhood was purchased by Jews who were expelled from Spain during the 16th century and came to Hevron under the leadership of Rav Malchiel Eshkenazi. They established a Jewish Quarter, which was built in the shape of a square, opening up to a shared courtyard. The houses served as a wall for the quarter. The Jewish Quarter could be reached by narrow paths and entrances that could easily be blocked in order to protect the community. The Jewish community thrived within its boundaries and included great rabbis and scholars, as well as tradesmen and businessmen. Over the generations, the Jewish Quarter became crowded and seven four-story high buildings were constructed. Despite the difficult conditions, The Jewish Quarter was very clean and organized and contained Torah institutions.
During the Arab Uprising (1929), many of the inhabitants of the neighborhood were cruelly tortured and killed by their Arab neighbors. The Jewish Quarter was robbed and vandalized.
After the Jordanian conquest (1948), the Jordanians destroyed the Jewish Quarter and established a marketplace, a garbage collection center, etc. Upon the ruins of the Avraham Avinu Synagogue a pen for animals was placed.
After the liberation of Hevron in 1967, there were attempts to restore the neighborhood. Professor BenZion Tavger, zl, stubbornly fought for the restoration of the Avraham Avinu Synagogue. He was joined in this effort by many other individuals. It took the government of Israel until 1976 to allow for the animal pen to be removed and the remains of the synagogue to be uncovered. After many continuous struggles, the Quarter was restored and the synagogue was rebuilt.
In 1997, after most of the city was given over to Arab control, the residents of the neighborhood were shot at by a sniper who fired from the Abu Sneineh Hill directly opposite the neighborhood. In the year 1999, the Nachum and Yehuda House was built, named after Nachum Haas and Yehuda Partosh, who were murdered by Arab terrorists.
Today, there are about 40 families residing in the Avraham Avinu neighborhood. The offices of the Jewish Settlement of Hebron, nursery schools and Beitar House (a hostel) are situated in the neighborhood.